总的来说，细胞凋亡的调节大致可以分为Caspase依赖的和不依赖的两类 。对Caspase的抑制，大多只能延缓细胞凋亡的过程，并不能完全避免凋亡的发生 。但是对于凋亡研究来说 ，Caspase仍然是其核心机制分子 。Caspase家族包含多种蛋白，其中Caspase-1和Caspase-4主要负责白介素前体的活化，并不直接参与凋亡信号的传递 。被称为凋亡启动蛋白的Caspase-2, -8, -9, -10和-12主要负责对执行者的前体进行切割 ，从而产生有活性的效应蛋白。Caspase-3, -6和-7则可以直接切割细胞核内或细胞质中的结构蛋白和调节蛋白，以执行凋亡程序。一般来说，PARP和Lamin A/C等靶蛋白可被活化的Caspase剪切，随后成为凋亡的标记 ，ROCK被切割后则会影响质膜稳定性，促进凋亡的发生。
| 凋亡相关靶标 | 产品货号 | 精品抗体 | 重组兔单抗 | 产品名称 | 反应种属 | 应用 |
| 死亡受体相关 | R24283 | √ | √ | Fas Rabbit mAb | Human | WB,IHC-F,IHC-P,ICC/IF |
| 501540 |
|
| TNF Receptor 1 Rabbit pAb | Human,Mouse,Rat | WB,IHC-P |
| 200822 | √ |
| TNFRSF10B (7F4) Mouse mAb | Human,Mouse | WB,ICC/IF |
| R24275 | √ | √ | FADD Rabbit mAb | Mouse,Rat | WB,IP |
| 820622 |
|
| FADD Rabbit pAb | Human,Mouse | WB,IHC-P,ELISA |
| R25279 | √ | √ | PARP1 Rabbit mAb | Human,Mouse,Rat | WB,IHC-F,IHC-P,ICC/IF |
| 380374 | √ |
| Cleaved-PARP1 Rabbit pAb | Human | WB,ICC/IF,IP,FC |
| R24823 | √ | √ | Lamin A/C Rabbit mAb | Human,Mouse,Rat | WB,IHC-F,IHC-P,ICC/IF,IP |
| R24647 | √ | √ | ICAD Rabbit mAb | Human,Rat | WB |
| R25607 | √ | √ | ROCK1 Rabbit mAb | Human,Mouse,Rat | WB,IP |
| R22622 | √ | √ | ROCK2 Rabbit mAb | Human,Rat | WB,ICC/IF |
| caspase凋亡启动子 | 381055 |
|
| Caspase 2 Rabbit pAb | Human,Mouse,Rat | WB,IHC-P,ICC/IF,FC |
| 250106 | √ |
| Caspase 8 (2G12) Mouse mAb | Human,Mouse,Rat | WB,IHC-F,IHC-P,ICC/IF |
| R22844 | √ | √ | Caspase 9 Rabbit mAb | Human,Mouse | WB,IP |
| 381238 |
|
| Cleaved-Caspase 9 Rabbit pAb | Human,Mouse | WB,IP |
| R23723 | √ | √ | Caspase 10 Rabbit mAb | Human | WB,IHC-P,IP |
| 160136 |
|
| Caspase 12 Rabbit pAb | Human,Mouse | WB,IHC-P,ELISA |
| caspase凋亡效应器 | R23315 | √ | √ | Caspase 3 Rabbit mAb | Human,Mouse,Rat | WB,IHC-P,IP |
| 380169 | √ |
| Cleaved-Caspase 3 p17 Rabbit pAb | Human | WB,IHC-P,ICC/IF |
| R26517 | √ | √ | Caspase 6 Rabbit mAb | Human | WB,IHC-P |
| 341036 |
|
| Cleaved-Caspase 6 p18 Rabbit pAb | Human,Rat | WB,IHC-P,ELISA |
| R26518 | √ | √ | Caspase 7 Rabbit mAb | Human,Mouse,Rat | WB,IHC-P |
| R27200 | √ | √ | Caspase 7 Rabbit mAb | Human | WB,IHC-P |
| caspase其他蛋白 | 381016 | √ |
| Caspase 1 Rabbit pAb | Human,Rat | WB,IHC-P |
| 341030 | √ |
| Cleaved-Caspase 1 Rabbit pAb | Human | WB,ICC/IF,IHC-F,IHC-P,ELISA |
| 381294 |
|
| Caspase 5 Rabbit pAb | Human | WB,IHC-P,ICC/IF,IP |
| 347416 |
|
| Cleaved-Caspase 4/5 p20 Rabbit pAb | Human | WB,ELISA |
| R23724 | √ | √ | Caspase 11 Rabbit mAb | Mouse | WB,IP |
| 线粒体相关 | R22867 | √ | √ | Cytochrome C Rabbit mAb | Human,Mouse,Rat | WB,IHC-P,IP |
| 380882 |
|
| APAF1 Rabbit pAb | Human,Mouse | WB,IHC-P,ICC/IF |
| 201149-8H1 | √ |
| AIF (8H1) Mouse mAb | Human | WB,ICC/IF |
| 382307 |
|
| Endo G Rabbit pAb | Human,Mouse,Rat | WB |
| R26117 | √ | √ | XIAP Rabbit mAb | Human,Mouse,Rat | WB |
| R25739 | √ | √ | SMAC Rabbit mAb | Human,Mouse,Rat | WB,IHC-F,IHC-P,ICC/IF,IP |
| 381426 | √ |
| ATF4 Rabbit pAb | Human,Mouse,Rat | WB,IHC-P,ICC/IF,IP,FC |
| 应激，DNA损伤相关 | R23316 | √ | √ | DDIT3 Rabbit mAb | Human,Mouse | WB,IHC-P |
| 381868 |
|
| Calpain 1 Rabbit pAb | Human,Mouse,Rat | WB,IHC-P,ICC/IF,FC |
| R24780 | √ | √ | JNK Rabbit mAb | Mouse,Rat | WB,ICC/IF,IP |
| R26311 | √ | √ | Phospho-JNK1 (Thr183/Tyr185) Rabbit mAb | Human | WB,IP |
| R25247 | √ | √ | p53 Rabbit mAb | Human | WB,ICC/IF |